Pathlab update: Coeliac disease algorithm change
Pathlab is updating its coeliac disease testing algorithm to improve efficiency while maintaining clinical accuracy.
From 11 November 2025, total IgA will no longer be tested upfront for all coeliac requests; instead, it will be added only when the initial anti-tTG IgA result suggests possible IgA deficiency. Anti-DGP IgG will continue to be added automatically when IgA is <0.05 g/L.